THE WORLD QUESTION CENTER 2005: Stuart Kaufmann writes

"Consider this, the number of possible proteins 200 amino acids long is 20 raised to the 200th power or about 10 raised to the 260th power. Now, the number of particles in the known universe is about 10 to the 80th power. Suppose, on a microsecond time scale the universe were doing nothing other than producing proteins length 200. It turns out that it would take vastly many repeats of the history of the universe to create all possible proteins length 200. This means that, for entities of complexity above atoms, such as modestly complex organic molecules, proteins, let alone species, automobiles and operas, the universe is on a unique trajectory (ignoring quantum mechanics for the moment). That is, the universe at modest levels of complexity and above is vastly non-ergodic."